We offer several different streams of injection therapy to primarily deal with inflammation. At Axis Foot and Ankle Clinic we use a combination of cortisone injections and prolotherapy to best meet the needs of our patients. Cortisone injections are the traditional way to reduce inflammation without the use of anti-inflammatory drugs. Unfortunately, cortisone injections can have long-term side effects. Prolotherapy however has next to no potential long-term side effects but it does require multiple injections, which can be painful.